Apert Syndrome
The Microsoft 365 Copilot app lets you create, share, and collaborate all in one place with innovative apps. Watch our educational video to learn more about the services and treatment options CHOP offers to children with craniofacial conditions such as Apert syndrome. Additionally, our Craniofacial Team maintains close collaboration with Genetics, Ophthalmology, Speech, Otolaryngology (ENT), Audiology and Neurosurgery to help provide comprehensive craniofacial care. At CHOP, our experienced Craniofacial Surgeons will help guide your child through craniosynostosis repair and other surgeries to address symptoms related to airway, dental/jaw relationships and craniofacial relations. The treatment of Apert syndrome is dependent upon both functional and appearance-related needs, and should be addressed immediately after your child is born.
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- With Apert syndrome, the skull is smaller than usual, which can put pressure on the developing brain.
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The characteristic feature that distinguishes Apert syndrome from other types of syndromic craniosynostosis is the presence of hand anomalies, most commonly fused or webbed fingers (syndactyly). Other common characteristics include large elongated forehead, shallow eye sockets causing prominent eyes, narrow palate with or without a cleft, fused bones in the arms, elbows and hips, and hearing loss. A doctor will check for additional complications caused by Apert syndrome and suggest appropriate treatments. With Apert syndrome, the skull is smaller than usual, which can put pressure on the developing brain. This article will provide an overview of Apert syndrome, including the symptoms, treatments, and outlook for this condition. This can cause a back-up of CSF and increase the blood pressure in the veins draining blood from the brain.
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Surgery is needed to prevent the closing of the coronal sutures from damaging brain development. It is still not very clear why people with Apert syndrome have both craniosynostosis and syndactyly. Other features of acrocephalosyndactyly may include shallow bony orbits and broadly spaced eyes. Due to the premature closing of the coronal sutures, increased cranial pressure can develop, leading to mental deficiency. This results in another common characteristic, a high, prominent forehead with a flat back of the skull.
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Apert syndrome complications and treatment
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Timeline of treatment
This surgery is usually performed when a child is between ages 6 and 8 months. Surgery to correct the abnormal connections between bones is the main treatment for Apert syndrome. Doctors often suspect Apert syndrome or another craniosynostosis syndrome at birth because of a newborn’s appearance. The defective gene in babies with Apert syndrome allows the skull bones to fuse together prematurely, a process called craniosynostosis. Apert syndrome has no cure, but surgery can help correct some of the problems that result. Cleveland Clinic’s health articles are based on evidence-backed information and review by medical professionals to ensure accuracy, reliability and up-to-date clinical standards.
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